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Predictive toxicogenomics approaches to non-genotoxic carcinogens

โœ Scribed by Michael McMillian; Alex Nie; Nandini Raghavan; Dhammika Amaratunga; Peter Lord


Book ID
119380652
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
49 KB
Volume
180
Category
Article
ISSN
0378-4274

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Toxicogenomics technology defines toxicity gene expression signatures for early predictions and hypotheses generation for mechanistic studies, which are important approaches for evaluating toxicity of drug candidate compounds. A large gene expression database built using cDNA microarrays and liver s