Predictive QSAR workflow for the in silico identification and screening of novel HDAC inhibitors
β Scribed by Georgia Melagraki; Antreas Afantitis; Haralambos Sarimveis; Panayiotis A. Koutentis; George Kollias; Olga Igglessi-Markopoulou
- Book ID
- 106468261
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 353 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1381-1991
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The 4.9-kb segment of the Chinese hamster hydroxymethylglutaryl-CoA reductase promoter found in pRedCAT-3 consists of 1.4-kb of the promoter and a 3.5-kb intron. We placed this segment upstream of a reporter gene, lacZ of E. coli. The new construct pRed3lacZ was transfected into human hepatoma cells