Background. Cervical lymph node metastasis has a major influence on survival in oral cancer. However, the factors influencing its occurrence are uncertain. Our aim was to improve the prognostic efficiency of the histologic assessment of the primary tumor in predicting metastasis in an individual pat
Predictive Markers for Late Cervical Lymph Node Metastasis in Patients with N0 Squamous Cell Carcinoma of the Tongue
โ Scribed by Hideo Kurokawa; Yoshihiro Yamashita; Shinobu Matsumoto; Koichi Takamori; Kaori Igawa; Koji Kashima; Min Zhang; Hiroshi Fukuyama; Tetsu Takahashi; Sumio Sakodal
- Book ID
- 117613264
- Publisher
- Scientific Communications
- Year
- 2006
- Tongue
- English
- Weight
- 203 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0915-6992
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Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase
## Background: Many histopathologic parameters in head and neck squamous cell carcinoma have been identified as predictive factors for cervical metastasis. several studies focused on tumor thickness, and the depth of invasion was suggested to have a relationship to the occurrence of cervical metast