Prediction of Type 1 Diabetes
β Scribed by Erlich, H. A.; Valdes, A. M.; Noble, J. A.
- Book ID
- 120183813
- Publisher
- American Diabetes Association
- Year
- 2013
- Tongue
- English
- Weight
- 146 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0012-1797
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π SIMILAR VOLUMES
In three children (patients 1, 2 and 3) insulindependency was predicted 28, 32 and 4 months, respectively before the disease became clinically manifest, by the finding of islet cell antibodies at that time. These retrospective findings support the evidence for a long pre-diabetic phase in childhood
## Abstract Type 1 diabetes is a disease characterised by disturbed glucose homeostasis, which results from autoimmune destruction of the insulinβproducing beta cells in the pancreas. The autoimmune attack, while not yet fully characterised, exhibits components of both misβtargeting and failed tole