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Prediction of the changes in thermodynamic stability of proteins caused by single amino acid substitutions

โœ Scribed by Demenkov, P. S. ;Aman, E. E. ;Ivanisenko, V. A.

Book ID
110156832
Publisher
Biophysical Society of Japan
Year
2006
Tongue
English
Weight
307 KB
Volume
51
Category
Article
ISSN
1349-2942

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## Abstract The adiabatic compressibility (ฮฒ~__s__~) was determined, by means of the precise sound velocity and density measurements, for a series of single amino acid substituted mutant enzymes of __Escherichia coli__ dihydrofolate reductase (DHFR) and aspartate aminotransferase (AspAT). Interesti