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Dramatic changes in the substrate specificities of prenyltransferase by a single amino acid substitution

✍ Scribed by Yuji Maki; Mariko Komabayashi; Yoshinori Gotoh; Norimasa Ohya; Hisashi Hemmi; Kazutake Hirooka; Tokuzo Nishino; Tanetoshi Koyama


Book ID
114395873
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
135 KB
Volume
19-20
Category
Article
ISSN
1381-1177

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## Abstract The adiabatic compressibility (Ξ²~__s__~) was determined, by means of the precise sound velocity and density measurements, for a series of single amino acid substituted mutant enzymes of __Escherichia coli__ dihydrofolate reductase (DHFR) and aspartate aminotransferase (AspAT). Interesti