Prediction of Docetaxel Response in Human Breast Cancer by Gene Expression Profiling
β Scribed by Chang, J.C.
- Book ID
- 123263846
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 57 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1043-321X
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## Abstract We studied the relationship between response of breast cancer to docetaxel (DOC) or cylophosphamide + epirubucin (CE) treatment and CYP3A4 mRNA expression in breast tumors. CYP3A4 inactivates DOC but not E, which is a predominant effector in CE treatment. Twenty patients with locally ad
## Abstract Promising results for prediction of outcome in breast cancer have been obtained by genome wide gene expression profiling. Some studies have suggested that an extensive overtreatment of breast cancer patients might be reduced by risk assessment with gene expression profiling. A patient g