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Predicting properties of intrinsically unstructured proteins

✍ Scribed by Joanne N. Bright; Thomas B. Woolf; Jan H. Hoh

Book ID: 114099271
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 634 KB
Volume: 76
Category: Article
ISSN: 0079-6107
DOI: 10.1016/s0079-6107(01)00012-8

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## Abstract Neurodegenerative diseases are complex, multifactorial disorders where misfolding of proteins cause aberrant protein–protein interactions. They are not usually characterized by specific mutations especially for nonfamilial disease types. Most of the causative proteins, however, are intr