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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

✍ Scribed by Peter E Wright; H.Jane Dyson


Book ID
115629638
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
258 KB
Volume
293
Category
Article
ISSN
0022-2836

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✍ Uversky, Vladimir N.; Longhi, Sonia πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley & Sons, Inc. 🌐 English βš– 278 KB πŸ‘ 1 views

The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin -dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. The 26S proteasome is made of two co