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Predicting methylation status of CpG islands in the human brain

✍ Scribed by Fang, F.; Fan, S.; Zhang, X.; Zhang, M. Q.

Book ID
111896840
Publisher
Oxford University Press
Year
2006
Tongue
English
Weight
220 KB
Volume
22
Category
Article
ISSN
1367-4803

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## Abstract Previous studies on esophageal squamous cell carcinoma (ESCC) indicated that it contains much dysregulation of microRNAs (miRNAs). DNA hypermethylation in the miRNA 5β€² regulatory region is a mechanism that can account for the downregulation of miRNA in tumors (Esteller, N Engl J Med 200