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Predicting DNA Duplex Stability from the Base Sequence

✍ Scribed by Kenneth J. Breslauer, Ronald Frank, Helmut Blöcker and Luis A. Marky


Book ID
123633040
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
879 KB
Volume
83
Category
Article
ISSN
0027-8424

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Many important applications of DNA sequence-dependent hybridization reactions have recently emerged. This has sparked a renewed interest in analytical calculations of sequence-dependent melting stability of duplex DNA. In particular, for many applications it is often desirable to accurately predict