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Precolumn derivatization of retinoic acid for liquid chromatography with fluorescence and coulometric detection

✍ Scribed by S. El Mansouri; M. Tod; M. Leclercq; M. Porthault; J. Chalom

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 447 KB
Volume: 293
Category: Article
ISSN: 0003-2670
DOI: 10.1016/0003-2670(94)85029-1

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## Abstract A rapid and sensitive HPLC enantioselective method with fluorescence detection was developed to determine (−)‐(__R__) and (+)‐(__S__) enantiomers of the metabolites of citalopram, demethyl‐ and didemethyl‐citalopram in plasma and brain tissue. This assay involves pre‐column chiral deriv