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Preclinical studies on [11C]TMSX for mapping adenosine A2Areceptors by positron emission tomography

✍ Scribed by Kiichi Ishiwata; Wei-Fang Wang; Yuichi Kimura; Kazunori Kawamura; Kenji Ishii

Publisher
Springer Japan
Year
2003
Tongue
English
Weight
629 KB
Volume
17
Category
Article
ISSN
0914-7187

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## Abstract Iodobenzamide (IMB) labeled with either [^11^C] or [^125^I] was studied in mice and baboons. Pharmacological studies demonstrated an in vivo binding profile compatible with D~2~ dopamine receptors. Mouse biodistribution studies with both [^11^C]IMB and [^125^I]IMB showed a similar brain