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Preclinical and clinical experience with dasatinib in philadelphia chromosome-negative leukemias and myeloid disorders

✍ Scribed by Srdan Verstovsek

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
172 KB
Volume
33
Category
Article
ISSN
0145-2126

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✍ Michael W. N. Deininger; Jorge Cortes; Ron Paquette; Byung Park; Andreas Hochhau πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 380 KB

## Abstract ## BACKGROUND. Clonal cytogenetic abnormalities (CCA) were detected in Philadelphia chromosome (Ph)‐negative cells in some patients with chronic myeloid leukemia (CML) who attained a cytogenetic response to imatinib mesylate. In some patients, CCA/Ph‐negative status was associated with