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Precipitin system detected in sera from patients with non-A, non-B hepatitis

✍ Scribed by Dr. Jay H. Hoofnagle

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
331 KB
Volume
7
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A precipitin system detected by immunodiffusion was identified using sera from patients with non‐A, non‐B hepatitis. This system resembled those described by other authors as serological tests for non‐A, non‐B antigens and antibodies. However, testing of sera from a large number of patients with acute and chronic liver diseases revealed that this precipitin system was not specific for non‐A, non‐B hepatitis. Further characterization of the precipitin system demonstrated that it did not represent a true antigen‐antibody reaction. Precipitin lines detected by immunodiffusion during the course of acute and chronic non‐A, non‐B hepatitis may not represent reactions specific for this disease.

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