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Post-Transfusion hepatitis: antigen/antibody systems correlated with non-a, non-b hepatitis

✍ Scribed by L.V. Chircu; M. Pezzella; V. Lacava; G. Ricci

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
305 KB
Volume
6
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

In seven patients post‐transfusion hepatitis (PTH) was due to non‐A, non‐B virus(es) (38.9% of all PTH, while 61.1% were due to hepatitis B virus (HBV). No clinical or biochemical differences were observed in non‐A, non‐B PTH when compared with PTH due to HBV, while incubation period was very ample, from 15 days to nine months (generally 45 days to two months). An antigen/antibody system was shared by five of our patients (their sera showed precipitin lines when assayed by immunodiffusion with known sources of antigen or antibody), while in one patient an antigen/antibody system was detected when onset serum was assayed with self‐recovery serum but not when assayed with known sources of antigen and antibodies, nor with sera of the other five patients. Antigen was detected during the first weeks of illness, antibody at recovery, for both systems. The results suggest that there may be at least two antigen/antibody systems correlated to non‐A, non‐B hepatitis, not necessarily linked to incubation period.

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