Formation of microparticulate protein po
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Sang-Do Yeo; Gio-Bin Lim; Pablo G. Debendetti; Howard Bernstein
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Article
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1993
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John Wiley and Sons
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English
β 590 KB
Gas antisolvent (GAS) expansion of dirnethylsulfoxide (DMSO) and N,N-dimethylformamide (DMFA) solutions with supercritical carbon dioxide was used to produce biologically active powders of insulin. Powders with 90% of the particles smaller than 4 prn and 10% smaller than 1 pm were obtained under all