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Precipitation: A powerful tool for continuous purification of monoclonal antibodies

โœ Scribed by Sommer, Ralf; Tscheliessnig, Anne; Schulz, Henk; Helk, Bernhard; Jungbauer, Alois

Book ID
125801339
Publisher
Elsevier
Year
2014
Tongue
English
Weight
66 KB
Volume
31
Category
Article
ISSN
1871-6784

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โœ Paul McDonald; Corazon Victa; Jayme N. Carter-Franklin; Robert Fahrner ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 160 KB ๐Ÿ‘ 2 views

## Abstract We evaluated the potential for polyelectrolyte induced precipitation of antibodies to replace traditional chromatography purification. We investigated the impact of solution pH, solution ionic strength and polyelectrolyte molecular weight on the degree of precipitation using the anionic