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Pre-operative combined 5-FU, low dose leucovorin, and sequential radiation therapy for unresectable recta cancer

โœ Scribed by Bruce D. Minsky; Alfred M. Cohen; Nancy Kemeny; Warren E. Enker; David P. Kelsen; Gary Schwartz; Leonard Saltz; James Dougherty; Joanne Frankel; Jill Wiseberg

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
913 KB
Volume
25
Category
Article
ISSN
0360-3016

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๐Ÿ“œ SIMILAR VOLUMES

The efficacy of preoperative 5-fluoroura
The efficacy of preoperative 5-fluorouracil, high-dose leucovorin, and sequential radiation therapy for unresectable rectal cancer
โœ Bruce D. Minsky; Joanne Frankel; Alfred M. Cohen; Warren E. Enker; Nancy Kemeny; ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 744 KB

Background. The encouraging results seen in patients who received postoperative combined modality therapy in the adjuvant setting have prompted increased interest in preoperative combined modality therapy for patients with unresectable rectal cancer. The authors report the local control and survival

Preoperative high-dose leucovorin/5-fluo
Preoperative high-dose leucovorin/5-fluorouracil and radiation therapy for unresectable rectal cancer
โœ Bruce D. Minsky; Nancy Kemeny; David P. Kelsen; Bonnie Reichman; Leonard Saltz; ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 732 KB

Twenty patients with primary or recurrent unresectable rectal cancer limited to the pelvis were entered on a Phase I trial of preoperative pelvic radiation therapy (RT) (5040 cGy) and two cycles of combined high-dose leucovorin (LV) and 5fluorouracil (S-FU), followed by surgery and ten cycles of pos

Acute toxicity of neoadjuvant bolus 5-FU
Acute toxicity of neoadjuvant bolus 5-FU/methotrexate and leucovorin rescue followed by continuous infusion 5-FU plus pre-operative radiation therapy for rectal cancer
โœ Bruce D. Minsky; John Conti; Alfred M. Cohen; David P. Kelsen; Len Saltz; Jose G ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 682 KB

We present an analysis of acute toxicity of 3 cycles of neoadjuvant bolus methotrexate (MTX) with leucovorin (LV) rescue plus bolus 5-FU, followed by continuous infusion 5-FU with concurrent pre-operative 5040 cGy, and post-operative bolus 5-FU/ LV in patients with rectal cancer. Nine patients (1: u