Twenty patients with primary or recurrent unresectable rectal cancer limited to the pelvis were entered on a Phase I trial of preoperative pelvic radiation therapy (RT) (5040 cGy) and two cycles of combined high-dose leucovorin (LV) and 5fluorouracil (S-FU), followed by surgery and ten cycles of pos
Preoperative 5-fluorouracil, low-dose leucovorin, and concurrent radiation therapy for rectal cancer
โ Scribed by Bruce Minsky; Alfred Cohen; Warren Enker; David Kelsen; Nancy Kemeny; David Ilson; Jose Guillem; Leonard Saltz; Joanne Frankel; John Conti
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 714 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0008-543X
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Background. The encouraging results seen in patients who received postoperative combined modality therapy in the adjuvant setting have prompted increased interest in preoperative combined modality therapy for patients with unresectable rectal cancer. The authors report the local control and survival
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