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Pre-mRNA splicing in disease and therapeutics

✍ Scribed by Singh, Ravi K.; Cooper, Thomas A.

Book ID: 119328760
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 650 KB
Volume: 18
Category: Article
ISSN: 1471-4914
DOI: 10.1016/j.molmed.2012.06.006

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## Abstract Recent genomewide analyses of alternative splicing (AS) indicate that up to 70% of human genes may have alternative splice forms, suggesting that AS together with various posttranslational modifications plays a major role in the production of proteome complexity. Splice‐site selection u