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Alterations of pre-mRNA splicing in human inflammatory bowel disease

✍ Scribed by Robert Häsler; Martin Kerick; Nancy Mah; Claus Hultschig; Gesa Richter; Frank Bretz; Christian Sina; Hans Lehrach; Wilfried Nietfeld; Stefan Schreiber; Philip Rosenstiel

Book ID
113582888
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
818 KB
Volume
90
Category
Article
ISSN
0171-9335

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## Abstract Recent genomewide analyses of alternative splicing (AS) indicate that up to 70% of human genes may have alternative splice forms, suggesting that AS together with various posttranslational modifications plays a major role in the production of proteome complexity. Splice‐site selection u