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Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine

โœ Scribed by Robert H Purcell; Hanh Nguyen; Max Shapiro; Ronald E Engle; Sugantha Govindarajan; William C Blackwelder; Doris C Wong; Jean-Paul Prieels; Suzanne U Emerson

Book ID
117431504
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
146 KB
Volume
21
Category
Article
ISSN
0264-410X

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A hepatitis B vaccine produced in yeast by recombinant DNA technology was evaluated using 5-micrograms and 10-micrograms doses in a randomized trial lasting 7 months in 110 male armed forces recruits aged 17-19 years. Results were compared to those of an identical trial of a plasma-derived vaccine.