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Antigenic determinants of hepatitis E virus and vaccine-induced immunogenicity and efficacy

โœ Scribed by Zhao, Qinjian; Zhang, Jun; Wu, Ting; Li, Shao-Wei; Ng, Mun-Hon; Xia, Ning-Shao; Shih, James Wai-Kuo

Book ID
118130492
Publisher
Springer Japan
Year
2012
Tongue
English
Weight
421 KB
Volume
48
Category
Article
ISSN
0944-1174

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Hepatitis A virus (HAV) strain HAV/HFS/GBM was adapted to and grown in human diploid fibroblast cells. The HAV was concentrated by ammonium sulphate precipitation and high-speed centrifugation. The virus was inactivated by beta-propiolacton and purified by sedimentation through a 20% solution of suc