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Pre-B-cell Colony-enhancing Factor (PBEF/Visfatin) Gene Expression is Modulated by NF-κB and AP-1 in Human Amniotic Epithelial Cells

✍ Scribed by C.E. Kendal; G.D. Bryant-Greenwood

Book ID: 113854123
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 519 KB
Volume: 28
Category: Article
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2006.03.011

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## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in