NF-κB-dependent synergistic regulation of CXCL10 gene expression by IL-1β and IFN-γ in human intestinal epithelial cell lines
✍ Scribed by Sunil Yeruva; Giuliano Ramadori; Dirk Raddatz
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 500 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0179-1958
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in
## We previously reported that chemokine Growth Regu lated Oncogene 1 (Gro 1) is over-expressed in murine squamous cell carcinoma (SCC) with metastatic tumor progression. The enhanced expression of Gro-1 gene by SCC is regulated by activation of nuclear factor-B (NF-B), leading to accelerated tumor