𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Practical total synthesis of 11-deoxydaunomycinone and the first total synthesis of 11-deoxydaunomycin

✍ Scribed by Yasumitsu Tamura; Shuji Akai; Hisakazu Kishimoto; Masayuki Kirihara; Manabu Sasho; Yasuyuki Kita

Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
288 KB
Volume
28
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The first total synthesis of the naturally derived second generation anthracycline, ll-deoxydaunomycin (2) is described. Key steps in the synthesis of 1 include an efficient construction of cc-hydroxy methyl ketone moiety at Cg-position, a highly stereoselective synthesis of c>-C7,9-diol, and the first successful use of Cl3-acetal derivative for the qlycosidation.

📜 SIMILAR VOLUMES

First total synthesis of 11-tellura ster
First total synthesis of 11-tellura steroids
✍ Malika Ibrahim-Ouali 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 233 KB

The first total synthesis of 11-tellura steroids was achieved via an intramolecular Diels-Alder cycloaddition of o-quinodimethanes as the key step.

First total synthesis of 11-oxa steroids
First total synthesis of 11-oxa steroids
✍ Frédéric Cachoux; Malika Ibrahim-Ouali; Maurice Santelli 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 95 KB

The first total synthesis of 11-oxa steroids was achieved via an intramolecular Diels-Alder cycloaddition of orthoquinodimethane as the key-step.

Total Synthesis of 11-Azasteroids.
Total Synthesis of 11-Azasteroids.
✍ Frederic Cachoux; Malika Ibrahim-Ouali; Maurice Santelli 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 153 KB
Stereoselective Total Synthesis of (11β)
Stereoselective Total Synthesis of (11β)-11-Methoxycurvularin
✍ Karuturi Rajesh; Vangaru Suresh; Jondoss Jon Paul Selvam; Dokuburra Chanti Babu; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 164 KB

## Abstract A simple and highly efficient stereoselective total synthesis of (11__β__)‐11‐methoxycurvularin (**5**), a polyketide natural product, was achieved. The synthesis commenced with a Cu‐mediated regioselective opening of (2__S__)‐2‐methyloxirane (**6**) and comprised a __Keck__ asymmetric

ChemInform Abstract: First Total Synthes
ChemInform Abstract: First Total Synthesis of 11-Oxa Steroids.
✍ Frederic Cachoux; Malika Ibrahim-Ouali; Maurice Santelli 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v