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Practical Issues in ADAMTS13 Testing and Emerging Therapies in Thrombotic Thrombocytopenic Purpura

โœ Scribed by Spero R. Cataland; Haifeng M. Wu

Book ID
117822247
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
394 KB
Volume
48
Category
Article
ISSN
1532-8686

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ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura
โœ Luca A. Lotta; Isabella Garagiola; Roberta Palla; Andrea Cairo; Flora Peyvandi ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 223 KB

Congenital thrombotic thrombocytopenic purpura (TTP) (also known as Upshaw-Schulman syndrome, USS) is a rare, life-threatening disease characterized by thrombocytopenia and microangiopathic hemolytic anemia, associated with the deficiency of the von Willebrand factor-cleaving protease (ADAMTS13) due