A polycrystalline sample of a new polymorph of the title compound, C~8~H~11~NO~2~, was produced during a variable-temperature X-ray powder diffraction study. The crystal structure was solved at 1.67 Å resolution by simulated annealing from laboratory powder data collected at 250 K. Subsequent Rietve
Powder study of 3-azabicyclo[3.3.1]nonane-2,4-dione 1-methylnaphthalene hemisolvate
✍ Scribed by Hulme, Ashley T ;Fernandes, Philippe ;Florence, Alastair ;Johnston, Andrea ;Shankland, Kenneth
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 329 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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3-Azabicyclo[3.3.1]nonane-2,4-dione (cyclohexane-1,3-dicarboximide, C 8 H 11 NO 2 ) forms a 1:1 solvate with acetic acid (C 2 H 4 O 2 ). The crystal structure comprises hydrogen-bonded chains containing alternating cyclohexane-1,3-dicarboximide and acetic acid molecules.
The biotransformation of (^)-bicyclo [3.3.1]nonane-2,6-dione by Aspergillus niger and Glomerella cingulata was investigated. The diketone was reduced to the ketoalcohol 2-endo-hydroxy-bicyclo[3.3.1]nonane-6-one and the diol endo,endo-bicyclo[3.3.1]nonane-2,6-diol respectively. Endo,endobicyclo[3.3.1
**Facile synthesis of derivatives of 2,4‐diphenyl‐3‐azabicyclo[3.3.1]nonane and 7,9‐diphenyl‐8‐azabicyclo[4.3.1]decane** The facile synthesis of hydantoins, cyanhydrins and aminonitriles derived from 2,4‐diphenyl‐3‐azabicyclo[3.3.1]nonanone and 7,9‐diphenyl‐8‐azabicyclo[4.3.1]decanone is described.