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Potentiation of the hypotensive effect of adrenomedullin in pregnant rats

โœ Scribed by Ikuko Makino; Kazuhiko Shibata; Yasuo Makino; Kenji Kangawa; Tatsuhiko Kawarabayashi


Book ID
114017596
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
264 KB
Volume
385
Category
Article
ISSN
0014-2999

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The association of nitric oxide (NO) with the hypotensive effects of adrenomedullin (AM) was investigated in anesthetized rats. Spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY) were used at 11-13 weeks of age. Blood pressure and heart rate were measured from the femoral