Potentiation of Balb/3T3 fibroblast proliferative response by interleukin-1 and epidermal growth factor
โ Scribed by Edward S. Kimball; M.Carolyn Fisher; Francis J. Persico
- Book ID
- 113134020
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 604 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0008-8749
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.
## Abstract The great majority of murine Balb/cโ3T3 fibroblasts in densityโinhibited, quiescent cultures disintegrate and die rapidly when cells are deprived of serum in the medium. Plateletโderived growth factor (PDGF, 5 ng/ml) used alone and insulinโlike growth factor (IGFโ1, 40 ng/ml) + epiderma
## Abstract Benzo[a]pyreneโtransformed Balb 3T3 cells (BP3T3) exhibit โnormalโ growth controls at low concentrations of serum. Epidermal growth factor (EGF) stimulates DNA synthesis and cell division in both Balb 3T3 and BP3T3 cells at physiological concentrations. The growth response of BP3T3 cell