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Potentiation of Antiproliferative Drug Activity by Lonidamine in Hepatocellular Carcinoma Cells

โœ Scribed by Ricotti, L. ;Tesei, A. ;Paola, F. De ;Milandri, C. ;Amadori, D. ;Frassineti, G.L. ;Ulivi, P. ;Zoli, W.


Book ID
127209431
Publisher
E.S.I.F.T. S.r.l.
Year
2003
Tongue
English
Weight
120 KB
Volume
15
Category
Article
ISSN
1120-009X

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The ability of lonidamine, an energolytic derivative of indazolecarboxylic acid, to modulate the cytotoxicity of cisplatin was investigated in human ovarian-cancer cell lines sensitive (A2780) or with experimentally induced resistance (A2780/cp8) to the alkylating agent. A 24-hr post-incubation with