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Potentiatied antitumor effectiveness of combined chemo-immunotherapy with Interleukin-12 and 5-fluorouracil of L1210 leukemia in vivo

✍ Scribed by Goł[acedil]b, J; Zagożdżon, R; Kamiński, R; Kozar, K; Gryska, K; Iżycki, D; Mackiewicz, A; Stokłosa, T; Giermasz, A; Lasek, W


Book ID
110054847
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
164 KB
Volume
15
Category
Article
ISSN
0887-6924

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Nine new organoplatinum (PO compounds, cyclophosphamide (CY), and 5-fluorouracil (FU) were used singly and in combination in treatment of advanced Ll210 leukemia in C57BL/6 X DBA/2 hybrid mice. In each experiment the Pt + CY dual combination was minimally supra-additive at the doses chosen. However,