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Potentially fatal interaction between colchicine and disulfiram

✍ Scribed by Shu-Chiao Chen; Ming-Chyi Huang; Chun-Chieh Fan


Book ID
116841633
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
89 KB
Volume
33
Category
Article
ISSN
0278-5846

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Certain interactions between disulfiram and benzodiazepines, especially diazepam and chlordiazepoxide, have previously been reported. The influence of disulfiram on the pharmacokinetics of alprazolam, a triazolobenzodiazepine, metabolized by hepatic microsomal oxidation, has been evaluated in 11 chr