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Potential histidine decarboxylase inhibitors. 1. .alpha.- and .beta.-Substituted histidine analogs

✍ Scribed by DeGraw, J. I.; Engstrom, J.; Ellis, M.; Johnson, H. L.

Book ID: 126249255
Publisher: American Chemical Society
Year: 1977
Tongue: English
Weight: 550 KB
Volume: 20
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00222a027

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## Abstract Some studies suggest that the histaminergic system plays an important role in learning and memory. However, the results seem to be controversial in many behavioral tasks. In the present study, we used HDC knockout (HDC‐KO) mice to investigate the effects of long‐term histamine deficienc