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Potential diuretic-.beta.-adrenergic blocking agents: synthesis of 3-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,4-dioxino[2,3-g]quinolines

✍ Scribed by Willard, Alvin K.; Smith, Robert L.; Cragoe, Edward J.


Book ID
121409981
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
923 KB
Volume
46
Category
Article
ISSN
0022-3263

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Synthesis of [1,4]dioxino[2,3-c]quinolin
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## Abstract The synthesis of [1,4]dioxino[2,3‐__c__]quinolines and [1,4]dioxepino[2,3‐__c__]quinolines with restrained conformation of the piperidine ring, which represent 1,2,3,4‐tetrahydroquinolines containing two heteroatom substituents at positions 3 and 4, is described. In addition, the applic