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Potential biomarkers for early detection of acute graft-versus-host disease

✍ Scribed by Gabriela Lochmanová; Lenka Jedličková; David Potěšil; Alexandra Tomancová; Jan Verner; Šárka Pospíšilová; Michael Doubek; Jiří Mayer; Zbyněk Zdráhal


Book ID
115561294
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
576 KB
Volume
6
Category
Article
ISSN
1862-8346

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Pathophysiology of acute graft-versus-ho
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Graft-versus-host disease (GVHD) has been the primary limitation to the wider application of allogeneic bone marrow transplantation (BMT). The pathophysiology of acute GVHD is complex and can be conceptualized to be a three-step process based on murine studies. In step 1, the conditioning regimen le