Potential Antitumor Agents, VII. 5-Substituted 6-Phenylimidazo[2,1-b]thiazoles
β Scribed by Aldo Andreani; Daniela Bonazzi; Mirella Rambaldi
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 286 KB
- Volume
- 315
- Category
- Article
- ISSN
- 0365-6233
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## Abstract The reaction of 4,5βdiphenylimidazolβ2βthione (**1**) with aromatic ketones **2aβi** using the acidified acetic acid method afforded the 4,5βdiphenyl(2βimidazolylthio)acetophenones **3aβh** in good yields. While, the cyclized product **4i** was obtained directly upon reaction of **1** w
Synthesis and Evaluation of 6-(Dibromomethyl)-5-nitropyrimidines as Potential Antitumor Agents. -A series of title compounds is synthesized, in case of (IX), (X), and ( XI) by unexpected substitution of the 4-methoxy group of (VII). Compound (X) and, especially, compound (XI) show good antiprolifer