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Potential antidepressants: 1-(2-(Methoxy- and hydroxyphenylthio)phenyl)-2-propylamines

✍ Scribed by Urban, Jiří; Šedivý, Zdeněk; Holubek, Jiří; Svátek, Emil; Ryska, Miroslav; Koruna, Ivan; Dlabač, Antonín; Valchář, Martin; Metyšová, Jiřina; Polívka, Zdeněk

Book ID
111985613
Publisher
UOCHB
Year
1990
Tongue
English
Weight
989 KB
Volume
55
Category
Article
ISSN
0010-0765

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## Abstract A series of 1‐[2‐[(2‐phenoxyphenyl)methoxy]ethyl]‐4‐(3‐phenylpropyl)piperazines 17–50 (Figure 1) were prepared and tested as inhibitors of biogenic amine re‐uptake. In our search for antidepressants, the relationship between their __in vitro__ and __in vivo__ activity as dopamine‐reupta