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Potential anticancer agents. XXVIII. Synthesis of Some Cyclohexanone Derived N-Nitrosoureas

โœ Scribed by Ileana Baracu; Dr. I. Niculescu-Duvaz


Book ID
105352938
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
370 KB
Volume
327
Category
Article
ISSN
1615-4150

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โœ Ping Ge; Richard A. Russell ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 465 KB

The simple anthracycline analogues 3a-e were synthesized as potential anticancer agents. Anodic oxidation of the phenol derivative 4, phthalide anion annelation ofp-quinone monoacetals 5 and selective attachment of the side chain were the three key steps towards these target compounds.