Potential Anticancer Agents. 1 XVI. Synthesis of 2-Deoxy-β-D-ribofuranosides via the 2,3-Episulfonium Ion Approach
✍ Scribed by Anderson, Charles D.; Goodman, Leon; Baker, B. R.
- Book ID
- 127146269
- Publisher
- American Chemical Society
- Year
- 1959
- Tongue
- English
- Weight
- 754 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0002-7863
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## Abstract The synthesis of 8‐aza‐1,3‐dideaza‐2′‐deoxyadenosine (3a) as well as of 4‐ and 5,6‐substituted benzotriazole 2′‐deoxy‐β‐D‐ribonucleosides is described (__Schemes 1–3__). Glycosylation of benzotriazole anions is stereoselective in all cases (exclusive β‐D‐anomer formation), but regioisom
Eight arsenic-containing ribosides were prepared from dimethyl( 1 -0-methyl1 -5-deoxy-2,3-0-isopropylidene-P-D-ribofuranos-5-yl)arsine and (2's)- Reactions of the arsines with sulfur produced the compounds with a (CH,),As=S group as substituent in the 5-position. Treatment of these dimethyl(ribosy1