𝔖 Bobbio Scriptorium
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Potential Anticancer Agents. 1 LI. Synthesis of 2-Amino-9-(5'-deoxy-β-D-ribofuranosyl)-9-H-purine-6-thiol

✍ Scribed by REIST, ELMER J.; HART, PHILLIP A.; GOODMAN, LEON; BAKER, B. R.


Book ID
127101981
Publisher
American Chemical Society
Year
1961
Tongue
English
Weight
670 KB
Volume
26
Category
Article
ISSN
0022-3263

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Synthesis of 3-(2-deoxy-β-d-ribofuranosy
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An unnatural base pair, 2-amino-6-(N,N-dimethylamino)purine (denoted x) and pyridin-2-one (denoted y), was designed to prove the structural requirements for base pair formation involving shape complementarity. It was expected that y might satisfy the structural requirements for pairing with x, in wh