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Potential and limitations of a γ34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS

✍ Scribed by McMenamin, M M; Byrnes, A P; Pike, F G; Charlton, H M; Coffin, R S; Latchman, D S; Wood, M J A


Book ID
110038197
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
616 KB
Volume
5
Category
Article
ISSN
0969-7128

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Identification and comparative sequence
✍ Millar Whalley; Graham Robertson; Christopher Bell; Daria Love; Martin Elphinsto 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 872 KB

A homologue of the herpes simplex virus (HSV) glycoprotein D gene has been identified in the genome of equine herpesvirus-1 (EHV-1, equine abortion virus). An open reading frame in the middle of the short unique (US) region is capable of encoding a polypeptide of 402 amino acids that has 26% and 20%