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Potent Inhibitory Ligands of the GRB2 SH2 Domain from Recombinant Peptide Libraries

โœ Scribed by Charles P. Hart; Jennifer E. Martin; Margaret A. Reed; Aftab A. Keval; Matthew J. Pustelnik; Jeffrey P. Northrop; Dinesh V. Patel; J.Russell Grove


Book ID
114284212
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
444 KB
Volume
11
Category
Article
ISSN
0898-6568

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ChemInform Abstract: Highly Potent Inhib
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Highly Potent Inhibitors of the Grb2-SH2 Domain. -The preparation of peptide mimetics (IX) (11 examples) with different substituents at the 3-indolyl-propylamine C-terminal group and their inhibition of the Grb2-SH2 domain is reported.