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Potent inhibition of human telomerase by helenalin

✍ Scribed by Pei-Rong Huang; Yuan-Ming Yeh; Tzu-Chien V. Wang

Book ID
116333494
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
201 KB
Volume
227
Category
Article
ISSN
0304-3835

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πŸ“œ SIMILAR VOLUMES

Inhibition of Human Telomerase by 7-Deaz
Inhibition of Human Telomerase by 7-Deaza-2β€²-deoxyguanosine Nucleoside Triphosphate Analogs: Potent Inhibition by 6-Thio-7-deaza-2β€²-deoxyguanosine 5β€²-Triphosphate
✍ Terace M. Fletcher; Brian E. Cathers; K.S. Ravikumar; Blain M. Mamiya; Sean M. K πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 487 KB

We have examined analogs of the previously reported 7-deaza-2Ј-deoxypurine nucleoside triphosphate series of human telomerase inhibitors. Two new telomerase-inhibiting nucleotides are reported: 6-methoxy-7-deaza-2Ј-deoxyguanosine 5Ј-triphosphate (OMDG-TP) and 6-thio-7-deaza-2Ј-deoxyguanosine 5Ј-trip