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Potent antitumor activity of a tumor-specific soluble TCR/IL-2 fusion protein

✍ Scribed by Heather J. Belmont; Shari Price-Schiavi; Bai Liu; Kimberlyn F. Card; Hyung-il Lee; Kai-ping Han; Jinghai Wen; ShaMay Tang; Xiaoyung Zhu; Jane Merrill; Pierre-Andre Chavillaz; Jeffrey L. Wong; Peter R. Rhode; Hing C. Wong


Book ID
113539416
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
643 KB
Volume
121
Category
Article
ISSN
1090-2341

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Augmented antitumor activity of a second
✍ Koichiro Nakahara; Tsuneaki Sakata πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 336 KB

## Abstract ## Background To enhance the antitumor efficacy of IL2 gene therapy, combinations of several other genes, such as p53, a tumor suppressor gene, or lymphotactin, a C‐chemokine, and the IL2 gene are attempted, and synergistic effects are observed. We report here on the enhanced antitumor