Potent anti-HIV activity of some phosphate derivatives of AZT
β Scribed by C. McGuigan; T.J. O'Connor; D. Curley; K.G. Devine; D.J. Jeffries; B.C.N.M. Jones; C. Nickson; R. Pathirana; D. Kinchington
- Book ID
- 118392524
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 51 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0166-3542
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π SIMILAR VOLUMES
The synthesis, in vitro anti-HIV activity and stability studies of the 5Π-fluorophosphate derivative of 3Π-azido-3Π-deoxythymidine (AZT) are reported. The results support the hypothesis that this phosphorylated entity exerts its biological effect via the delivery of the corresponding 5Π-mononucleoti
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