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Potency of insulin analogs for in situ stimulation of glucose uptake in rat soleus muscle

✍ Scribed by NL Eleid; RB Weinstein; IB Brodsky; MA Heffner; MP O'Keefe; JA Takeuchi; ME Tischler


Book ID
114364250
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
129 KB
Volume
124
Category
Article
ISSN
1095-6433

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Cycloheximide (20-200 mg/l) did not affect basal D-[U-14C]xylose uptake by rat soleus muscle (2.4 +/- 0.2 mumol . g-1 . h-1). However, the stimulatory effect of insulin on sugar transport was progressively reduced from 375% above basal in control muscles to 170% in muscles exposed to 200 mg cyclohex