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ATP depletion promotes deactivation of insulin-stimulated sugar transport in rat soleus muscle

โœ Scribed by Robert E. Kaldawi; Kin Tak Yu; Michael K. Gould


Book ID
115705722
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
540 KB
Volume
226
Category
Article
ISSN
0003-9861

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โœ J. R. Forsayeth; M. K. Gould ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 443 KB

Cycloheximide (20-200 mg/l) did not affect basal D-[U-14C]xylose uptake by rat soleus muscle (2.4 +/- 0.2 mumol . g-1 . h-1). However, the stimulatory effect of insulin on sugar transport was progressively reduced from 375% above basal in control muscles to 170% in muscles exposed to 200 mg cyclohex