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Pot, atom and step economic synthesis: a diversity-oriented approach to construct 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones

✍ Scribed by Xiang, Haoyue; Chen, Yanhong; He, Qian; Xie, Yuyuan; Yang, Chunhao


Book ID
127328724
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
360 KB
Volume
3
Category
Article
ISSN
2046-2069

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A One-Pot Biginelli Synthesis of 6-Unsub
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## Abstract The three‐component __Biginelli__‐like cyclocondensation reaction of enamines **1**, urea, and aldehydes in dioxane/acetic acid efficiently afforded the corresponding 6‐unsubstituted 3,4‐dihydropyrimidin‐2(1__H__)‐ones **2** in good yields (__Scheme 1, Table__). The corresponding reacti